io.github.cyanheads

chembl-mcp-server

Link compounds to protein targets, rank bioactivity, and look up drug mechanisms and indications.

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Package Details

Transportstdio
Runtimebun

Package Arguments

Positional
Position 0
run
Position 1
start:stdio

Environment Variables

CANVAS_PROVIDER_TYPE(str)
Default:none

Set to 'duckdb' to enable the bioactivity DataCanvas spill and the chembl_dataframe_* SQL tools. When 'none', large bioactivity sets inline a preview but never spill.

CHEMBL_API_BASE_URL(str)
Default:https://www.ebi.ac.uk/chembl/api/data

Base URL for the ChEMBL REST data API. Override for a private mirror or pinned host.

CHEMBL_REQUEST_TIMEOUT_MS(str)
Default:30000

Per-request timeout in milliseconds for upstream ChEMBL fetches.

CHEMBL_MAX_PAGE_SIZE(str)
Default:1000

ChEMBL per-page cap when streaming activity pages for the bioactivity spill (max 1000).

CHEMBL_DEFAULT_LIMIT(str)
Default:25

Default result limit applied when callers omit it.

CHEMBL_DATAFRAME_DROP_ENABLED(str)
Default:false

Set to 'true' to register the opt-in chembl_dataframe_drop tool (absent from tools/list when off).

MCP_LOG_LEVEL(str)
Default:info

Sets the minimum log level for output (e.g., 'debug', 'info', 'warn').

TransportStreamable HTTP
Runtimebun

Package Arguments

Positional
Position 0
run
Position 1
start:http

Environment Variables

MCP_HTTP_HOST(str)
Default:127.0.0.1

The hostname for the HTTP server.

MCP_HTTP_PORT(str)
Default:3010

The port to run the HTTP server on.

MCP_HTTP_ENDPOINT_PATH(str)
Default:/mcp

The endpoint path for the MCP server.

MCP_AUTH_MODE(str)
Default:none

Authentication mode to use: 'none', 'jwt', or 'oauth'.

MCP_LOG_LEVEL(str)
Default:info

Sets the minimum log level for output (e.g., 'debug', 'info', 'warn').

CANVAS_PROVIDER_TYPE(str)
Default:none

Set to 'duckdb' to enable the bioactivity DataCanvas spill and the chembl_dataframe_* SQL tools. When 'none', large bioactivity sets inline a preview but never spill.

CHEMBL_API_BASE_URL(str)
Default:https://www.ebi.ac.uk/chembl/api/data

Base URL for the ChEMBL REST data API. Override for a private mirror or pinned host.

CHEMBL_REQUEST_TIMEOUT_MS(str)
Default:30000

Per-request timeout in milliseconds for upstream ChEMBL fetches.

CHEMBL_MAX_PAGE_SIZE(str)
Default:1000

ChEMBL per-page cap when streaming activity pages for the bioactivity spill (max 1000).

CHEMBL_DEFAULT_LIMIT(str)
Default:25

Default result limit applied when callers omit it.

CHEMBL_DATAFRAME_DROP_ENABLED(str)
Default:false

Set to 'true' to register the opt-in chembl_dataframe_drop tool (absent from tools/list when off).